Studiene fant at i de fleste tilfeller var de høyere dosene mindre effektive enn 1 mg-dosen og hadde mer destructive bivirkninger. Maksimal anbefalt dose er four mg for every dag.Distribusjonsvolumet vil være ca. 5 liter hos et voksent menneske for et legemiddel som hovedsakelig befinner seg i plasma.Reserver samtidig forskrivning av disse legemi
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